Every year, hundreds of thousands of women die from cervical cancer, even though it is one of the most preventable cancers. Why? In many low- and middle-income countries, women face barriers such as limited access to healthcare, long travel distances, time constraints, and lack of awareness. As a result, many women are never screened until the disease is advanced. This thesis explored whether self-sampling, a method where women collect a sample themselves, could help overcome these barriers. The study included women from Cambodia, Ethiopia, Mozambique, and Uganda to understand their experiences and preferences. The findings were encouraging: 90% of women said they would be willing to use self-sampling in the future. They described it as easy, quick, and more private than traditional gynaecological examinations. However, the study also revealed a critical gap: many women had never heard of HPV, the virus that causes cervical cancer, or the vaccine that can prevent it. These findings offer valuable insights for public health efforts aimed at improving cervical cancer prevention. Self-sampling has the potential to make screening more accessible, especially for women in remote or underserved areas. Yet, willingness alone is not enough; raising awareness and providing clear, accessible information remains essential to help more women understand the risks and take action to protect their health. By combining insights on self-sampling with the need for education, this research contributes to a growing body of evidence supporting more accessible and inclusive approaches to cervical cancer screening in vulnerable communities.