Hydrogel coatings for flexible neural probes: an optimization study
El Bakkali Younes, 2025
This research focuses on improving soft neural probes that can be safely implanted into the brain. These probes are designed to be both flexible and strong enough to avoid bending or breaking during surgery. One of their promising applications is in optogenetics, a technique that uses light to control specific brain cells. This method holds potential for treating neurological disorders, including epilepsy. For patients with epilepsy, optogenetic stimulation could one day allow for highly targeted control of seizure activity, reducing the need for medication or invasive surgery. By improving the mechanical stability of these probes, this work helps move the technology closer to real-world use, making brain implants safer and more reliable for long-term applications. The expected societal benefits are primarily in the medical and biotech sectors, supporting clinicians, patients, and medical device developers. Enhanced implant safety and simpler fabrication methods could make advanced treatments more accessible, not only in specialized hospitals but eventually in broader healthcare systems. Overall, this study contributes to the foundation for next-generation brain therapy tools that may improve the quality of life for people with epilepsy and other neurological conditions, offering more precise and biocompatible options in the future.
| Promotor | Jeroen Missinne |
| Opleiding | Biomedische Wetenschappen |
| Domein | Neurosciences |