This study delves into the idea of life engagement within the realm of nephrology treatment, particularly focusing on individuals dealing with Chronic Kidney Disease (CKD) in Belgium. Through the use of an ethnographic method, the research aims to gain insight into the first hand experiences of these patients and how incorporating life participation can enhance their overall well-being and medical results. The study commences by conducting a thorough examination of previous literature surrounding life engagement, chronic kidney disease (CKD), and the application of ethnography in medical research. This establishes a theoretical foundation for comprehending the intricate relationship among these elements and lays the groundwork for the practical investigation. The study entails conducting thorough interviews and observations at a nephrology center in Belgium, emphasizing the empirical aspect. By approaching the research from an ethnographic perspective, the study brings to light the various hurdles CKD patients encounter on a daily basis and how their illness hinders their engagement in daily activities. The results indicate that the importance of life participation for the well-being of patients is frequently neglected in traditional nephrology treatment. By prioritizing life participation, healthcare professionals can cater to the comprehensive needs of individuals with CKD, ultimately enhancing both their quality of life and health results. The study ends by examining the implications of these discoveries on nephrology care and suggesting ways to incorporate life participation into caregiving procedures. It also emphasizes the possibility of additional research in this field, especially in relation to other long-term illnesses. This thesis adds to the expanding knowledge of life participation and Chronic Kidney Disease, highlighting the importance of using an ethnographic approach in healthcare studies. It promotes the idea of reorienting nephrology care towards a patient-centered approach that emphasizes life participation as a crucial aspect of patient well-being. This change could have a significant impact on the quality of life for CKD patients, allowing them to experience more fulfilling lives despite their illness.